John R. Duchek, Ph.D.
Duchek Consulting Services LLC
158 Comrey Circle
PO Box 931
Carrizozo, NM, 88301
Phone: (505) 648-2868
or
5793 Karamar Drive
Saint Louis, MO 63128
Phone: (314) 845-3977
E-mail: johnduchek@duchekconsult.com


Specialties:

Pharmaceutical

Organic Chemistry

Troubleshooting

Molecular Modeling

Expert Witness

Patent:

Short Projects:

Need a starting material made? Need a reaction analyzed? Don't have the manpower? Arrangements can be made for me to work in your lab for stretches up to several months as a synthetic chemist



Patents/Professional Publications:

  1. Cannabinoid Crystalline Derivatives and Process of Cannabinoid Purification, John R. Duchek, Mallinckrodt Inc., US 7,402,686 B2, July 22, 2008, IN patent 219273,
  2. Crystal Structure of p-Tosyl-D9 -THC, Wassem Gul, Paulo Calvalho, Desmond Slade, John R. Duchek, David W. Berberich, David J. Kimmich, Mitchell A. Avery, Mahmoud A. ElSohly, in press May, 2008, Acta Crystallographica Section C, Crystal Structure Communications
  3. Process for the Preparation of (+)-P-Mentha-2,8-dien-1-ol, John R. Duchek, Hong Gu, Kendall Kilgore, US 7,323,607 B2, Jan 29, 2008, Mallinckrodt Inc.
  4. Synthesis of compounds useful in the manufacture of ketorolac, Henry Buehler, Douglas Caskey, John R. Duchek, US 6,559,319, May 6, 2003, Mallinckrodt Inc.
  5. Synthesis of compounds useful in the manufacture of ketorolac, Henry Buehler, Douglas Caskey, John R. Duchek, US 6,376,681, April 23, 2002, Mallinckrodt Inc.
  6. Synthesis of compounds useful in the manufacture of ketorolac, Henry Buehler, Douglas Caskey, John R. Duchek, US 6,489,491, Dec 3, 2002, Mallinckrodt Inc.
  7. Computational Study of Opioid Analogs: Development of 3-D QSAR models for delta, mu, and kappa opioid receptor binding affinities, Poster presented at the Spring, 2000 ACS meeting in San Francisco. Anil C. Nair, Seong-Jae Yu, William J. Welsh, John Duchek, Neile Grayson.
  8. Method of Preparing D-Propoxyphene, John R. Duchek, European Publication No. WO 90/14331, US 5,312,970, May 17, 1994, Mallinckrodt Inc.
  9. Dynamic Resolution of 3-Dimethylamino-2-methylpropiophenone (3-DAMP), John R. Duchek, U.S. 5,227,526, July 13, 1993, Mallinckrodt Inc.
  10. Facilitation of Electrochemical Oxidation of Dialkyl Sulfides Appended with Neighboring Carboxylate and Alcohol Groups, Richard S. Glass, Amorn Petsom, Massoud, Hojjatie, Brian R. Coleman, John R. Duchek, Jacob Klug, George S. Wilson, J. Amer. Chem. Soc., 110(14), 4772-8, (1988)
  11. "Biological Buffers”, J. R. Duchek, Aldrichimica Acta, 16, 2, (1983)
  12. "Erythrosin and pH Gradient Induced Photo-voltages in Bilayer Membranes", W. E. Varnadore, Jr., R. T. Arrieta, J.R. Duchek, J. S. Huebner, J. Membrane Biol., 65, 147-153, (1982)
  13. "Synthesis and Characterization of 2-substituted 6-methylthiobicyclo-[2.2.1]heptanes", Richard S. Glass, John R. Duchek, Usha Devi Prabhu, William N. Setzer, George S. Wilson, J. Org. Chem.,45, 3640, (1980)
  14. "Voltage Transients from Photoisomerizing Azo Dye in Bilayer Membranes", J. R. Duchek, J. S. Huebner, Biophysical Journal, 27, 317, (1979)
  15. "Lipid and Salt Effects on Carbocyanine Dye Induced Photo-voltages in Bilayer Membranes", J. A. Baker, J. R. Duchek, R. L. Hooper, R. J. Koftan, J. S. Huebner, Biochemica et Biophysica Acta, 553, 1-10, (1979)
  16. "Facilitation of Dialkylsulfide Oxidation by Neighboring Groups", Richard S. Glass, John R. Duchek, Jacob T. Klug, George S. Wilson, J. Amer. Chem. Soc., 99, 7349, (1977)
  17. "The Structure of Dehydromethionine. An Azasulfonium Salt", Richard S. Glass, John R. Duchek, J. Amer. Chem. Soc., 98, 965, (1976)
  18. Dissertation: "The Synthesis and Reactions of 3,4-Benzo-6-methyl-1,2,5-oxathiazine- 2,2-dioxide", St. Louis University, 159 pp. (1975)