PhaRmaB was established in October 2010 to provide a platform from which Dr. Bernstein could respond to requests for his services. Medicinal Chemistry: PhaRmaB provides world-class expertise in all phases of small molecule drug discovery including: Target Identification, Lead Identification [Hit-to-Lead], Lead Optimization, Candidate nomination, Clinical Candidate support and post launch product support. The company president’s experience includes: structure-based design, screening libraries design, privileged structures, optimization of DMPK parameters with reduction of off-target activities and as drug target areas: G-protein coupled receptors, enzyme inhibitors, ion-channel ligands, transporter inhibitors and nuclear hormone modulators. Due diligence: PharmaB LLC has experience in drug licensing, including due diligence activities. Services include third-party evaluation of lead and/or candidate structure and data. Portfolio Review: Dr. Bernstein has extensive experience in senior level project and portfolio reviews in many functions including: neuroscience, psychiatry, pain, respiratory, inflammation, oncology, safety assessment, and core chemical sciences. Expert Witness: PharmaB LLC provides expert witness support for patent litigation.